I am able to run around when doing serious combat grinding with ~700 health using the following:

• Two combat skills at level 80 (skills give you bonuses to max HP)
• Disappointing Corn Surprise (easy high level food to create)
• Endurance level 60
• Ruggedizer
• Make Me Strong Juice (depends on situation)
• Alcohol barrel buff of either +15 or maybe ~25 HP? (again, different buffs for different situations)
• Rubywall Crystal +Inv gear
• Symbol of Hate Made Manifest Amulet? +60 Health and like -30 Power?

When you hit level 30-40 and have some time, go to the Ranlon Cave and just tank Ranlon for an hour every couple of levels and you'll find yourself keeping Endurance closer to your skill level. Also, the Fae Bears in Eltibule and fighting and surviving the bears in the Fae Realm itself can be beneficial. The Animal Nexus cave also has some hard-hitting bears.

If you carry and use Ruggedizers, keep in mind you might want to also bring an UnPig Juice along with you. I've been using Ruggedizers for ~1 year in casual play and I've turned into a Pig maybe twice. When the game says that it is rare, it really is pretty rare. I think it's a worthwhile buff to always have on you, honestly, just make sure you farm up some unpig juices first.

There is an amulet (or ring, maybe?) that gives you +60 HP at a cost of a -30 or something to Power, I think. If you use Snacks and Nature Appreciation buffs from flowers, you aren't going to have an issue with Power, so it really just turns out to be a free +60 Health buff. I would highly recommend using that amulet, even if it's at level 50-60 and you have combat skills at 80. I am using one right now with next to no plans to update to a newer Amulet as the level 70 and 80 Amulet base stat changes just plain suck in comparison. Honestly, I'd probably still use this Amulet even if it was only a +30 Health buff.

Early players will have options like Windstep Shoes (+2 Sprint) and an Amulet of the Rugged Traveler (+1 Sprint) available to them if they need Sprint speed, but there are further buffs and changes that mid and high level players have that are worth noting as many players may not realize just how easy some of the early travel options can be obtained.

One such buff comes from Shamanic Infusion, the level 46 ability – Shaman's Deer Foot Infusion – will provide a +1.5 Sprint Speed bonus. When playing Psychology, you can also get speed buffs for when one of the abilities, Positive Attitude, is on cooldown and one such buff (+4 Sprint) is on boot items, meaning that you could have the buff on a collected pair of Windstep Shoes around level 40 or so, when you should be partaking in Casino Daily runs where you are likely to get such shoes. If you put the Shamanic Infusion buff on a pair of these, you will have a whopping 2 + 4 + 1.5 = +7.5 Sprint from just one item alone. (It's important to note that you can get a +4 Sprint from Positive Attitude to your helm item as well.)

Another notable Sprint option for mid-game and on comes from Battle Chemistry. While Battle Chemistry isn't available till after you have hit level 50 in Alchemy, most players won't have much difficulty doing that unless they completely neglect the skill and buying cheap components for leveling it off of vendors. Once you do have the skill, the “grind” to get to level 29 isn't difficult at all and can mostly be done in a single afternoon if you already have a high level secondary ability. At level 29, you will have access to the Extra Toes 2 ability which will give you an ability you cast after you enter every new zone to have an additional +3 Sprint while in that zone. There is also a temporary Haste Concoction ability that you can use every so often for an addition +6 Sprint burst.

Other abilities with speed buffs include Shield, Druid, Fire Magic, Lycanthrophy, and most of the animal forms have at least one speed option. You can see more on the wiki Haste page here.

Just remember to build at least one “Travel Loadout” that is designed to have high Inventory and Sprint on it, bind it and your combat loadout to keys (I use [, ], and \), and you can switch between combat skills and that loadout as needed.